Most of us have heard of biopharmaceuticals in the past, and almost all of us have used them at some point in our lives, but what are they? In simple terms, the word biopharmaceutical refers to biological, medical products. This includes vaccines, allergenic that treat allergies, blood and blood components, body tissues and cells, living cells used in cell therapy, and recombinant therapeutic proteins.
While many of us have used biopharmaceutical drugs in the past, most are unsure how they are produced. As well as this, we are uncertain of what is involved in making these life-saving products. One step in the production of biopharmaceuticals is cell line engineering. Keep reading below to find out all about what cell line engineering is and why it is such a crucial step in the development of drugs:
The Challenge of Developing Biopharmaceuticals
Developing new biopharmaceuticals is much more complex than you would expect. In fact, progressing a drug from target validation to market authorization can take an extremely long time and a tremendous amount of work.
Before developing new biopharmaceuticals, producers must consider many things. This includes things like how they will access the best controls and how they will reduce the time and cost of developing their biopharmaceutical products.
While this may be true, the good news is that there are usually ways to overcome any issues. For example, biopharmaceutical companies can use knockout cell lines to overcome the challenge of accessing the correct controls. As well as this, they can reduce the amount of time and money spent on developing their new biopharmaceutical by using cell line engineering. This is the quickest and most cost-effective option available.
What is Cell Line Engineering?
The first step in producing biopharmaceutical products, such as the ones listed above, is cell line engineering or cell line development. It examines the efficiency of in vitro testing, drug discovery, and toxicity.
The Benefits of Cell Line Engineering
In the past, it often took many months or years to develop and produce biopharmaceutical products. However, this is no longer the case thanks to recent technological advancements by cell line development experts. In fact, biopharmaceuticals can now be assessed at the early development stage, which can save a lot of time and money.
While this might not sound important, it is. This is because drugs that take a long time to produce and cost too much money are unlikely to reach our shelves. Instead, they only make it to the clinical trial phase. This means we miss out on many biopharmaceuticals that could be significant in treating diseases like cancer.
Biopharmaceuticals were first introduced in 1982, and since then, they have revolutionized the treatment of many severe medical conditions and diseases. However, developing biopharmaceuticals is a complicated process, which can take a lot of time, effort, and money to get right. Thankfully, each year we see new innovative technology that can help speed up the drug development process. One example of this is cell line engineering. Let’s hope that even more technology becomes available in the future to speed up and reduce the cost of producing new biopharmaceuticals.